Hotel Isis is a comfortable space located near the southern axis of the capital. It is well connected with the Estación Sur bus station in Mendéz Álvaro and the Planetarium both by metro and by car, since the M-30 bypass runs parallel to the Manzanares River bank. Also a short distance away is Parque de San Isidro, where the festivals honouring the patron saint of Madrid take place every year on May 15th.

Its premises house 82 spacious and comfortable rooms, both single and double rooms, a suite with a hydro-massage tub, a social room with capacity for 50 people, a parking garage and an annex for tall vehicles and, during the summer months, an outdoor sun deck from which guests can enjoy the beautiful views of the city. Furthermore, Hotel Isis includes a cosy restaurant decorated in a rustic and traditional style, in which delicious Spanish dishes are served daily.